(01) DEUTERIUM OXIDE VALIDATION OF BIOIMPEDANCE TOTAL BODY WATER ESTIMATES IN HISPANIC ADULTS

Saturday, July 15, 2023

8:30 AM – 8:45 AM East Coast USA Time

Location: Milano I-II

Podium Presenter(s)

Ayush Mehra (he/him/his)

Undergraduate Research Assistant
The Ohio State University
Dublin, Ohio, United States

Author(s)

CS

Catherine Saenz

Exercise Science
College of Education and Human Ecology, The Ohio State University, OH, USA
Columbus, Ohio, United States
Grant M. Tinsley, PhD, CSCS,*D

Associate Professor
Texas Tech University
Lubbock, Texas, United States
KP

Kyung-Shin Park

Associate Professor
Texas A&M International University
Laredo, Texas, United States
BN

Brett S. Nickerson

Associate Professor
The Ohio State University
Columbus, Ohio, United States

Abstract Details: To date, bioimpedance device body composition assessments in Hispanics have primarily focused on body fat percent, fat mass, and fat-free mass (FFM) instead of total body water (TBW). While numerous bioimpedance devices are available for use in research, clinical, fitness, and athletic settings, there is limited information available on which type of bioimpedance device is preferred for TBW assessments in Hispanic populations.

Purpose: The purpose of this study was to validate multiple bioimpedance devices for the estimate of TBW in Hispanics adults when using a criterion D2O technique.

Methods: One-hundred thirty individuals (males: n=70; females: n=60) of Hispanic descent had TBW estimated via deuterium oxide (D2O), single-frequency bioimpedance analysis (SF-BIA), multi-frequency bioimpedance analysis (MF-BIA), and bioimpedance spectroscopy (BIS).

Results: The mean values for SF-BIA were significantly lower than D2O when evaluating the entire sample (37.4L and 38.2L, respectively; p< 0.05). In contrast, TBW values were not statistically significant when comparing D2O against MF-BIA and BIS (38.1L and 38.4L, respectively; both p >0.05). Bland-Altman analysis indicated no proportional bias when evaluating the entire sample. However, the slope and intercept for MF-BIA slightly differed from the line of identity. The standard error of estimate and total error values were ≤ 2.3L and Lin’s concordance correlation coefficient were ≥0.96 for all comparisons.

Conclusions: Multiple commercially available bioimpedance technologies hold promise for accurate estimation of TBW in Hispanic adults. While all methods demonstrated relatively low errors relative to the D2O criterion, BIS exhibited the most consistent performance, particularly at the group level. These findings provide essential information for researchers and clinical nutrition practitioners assessing TBW in Hispanic adults. PRACTICAL APPLICATIONS: Prior to the current study, limited research has systematically determined the accuracy of various bioimpedance devices for hydration. The assessment of TBW is an important component of body composition assessments since hydration comprises the largest component of FFM. Accordingly, p</span>ractitioners that have access to various bioimpedance devices may consider using BIS over SF-BIA and MF-BIA, when available. Nonetheless, practitioners with limited access to SF-BIA and MF-BIA may still use these methods for TBW assessments.

Acknowledgements: Research reported in this publication was supported by the National Institute of General Medical Sciences of the National Institutes of Health under Award Number SC1GM135099. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.